BLAST
UP
core
NCBI BLAST remote search
HMMER
UP
core
Pfam domain scan
Phobius
UP
core
Signal peptide and TM topology
CDD
UP
core
NCBI conserved domains
ScanProsite
UP
core
Patterns and functional sites
UniProtKB features
UP
core
Curated UniProt positional features for domains, motifs, regions, and sites
Coils
DOWN
core
LUPAS coiled-coil prediction
SMART
UP
experimental
Best-effort HTML parsing
InterProScan
UP
slow
Broad integrative annotation
SignalP
OFFLINE
offline
Upstream endpoint currently unavailable
DisorderPred
UP
companion
Companion disorder profile using NetSurf plus IUPred3 / ANCHOR2 comparison.
SSPred consensus
UP
companion
Optional secondary-structure consensus bundle using the SSPred service adapters.